Inter Miami CF vs. Seattle Sounders FC Prediction, Match Preview and Betting Tips, 17 September 2025

Get ready for a thrilling clash as Inter Miami CF takes on Seattle Sounders FC in round 18 of Major League Soccer at Chase Stadium. This encounter is critical with both teams closely matched in the league standings—Inter Miami sitting 11th with 46 points, and Seattle Sounders just a step behind at 12th with 45 points.

Inter Miami will be keen to bounce back from a heavy 3-0 defeat to Seattle in the recent Leagues Cup Final Stage. With Lionel Messi spearheading the attack, having netted 19 goals this season, the home side has the upper hand, given their solid home form. They’ve scored in 81% of their matches this season, and Lionel Messi’s performance will be pivotal for the home side.

Seattle Sounders, on the other hand, are in an impressive run, boasting an unbeaten streak of five games, including a dominating 3-0 win against Inter Miami just weeks ago. Danny Musovski, their top scorer with 14 goals, will be the key player to watch.

Given both teams’ defensive vulnerabilities, especially conceding goals in the 31-45 minute interval, our match tips suggest a bet on both teams to score. This fixture promises a highly competitive affair with plenty of goals expected.

Inter Miami CF vs Seattle Sounders FC Prediction & Betting tip

Inter Miami CF vs Seattle Sounders FC Prediction
Betting tip	Odds
Both Teams to Score (Yes)	1.97

Why this prediction is solid:

1. Inter Miami CF’s Scoring Pattern: Inter Miami has seen both teams score in 73% of their matches this season, showing a high likelihood that both sides will find the net.
2. Seattle Sounders’ Recent Form: Seattle Sounders have netted 13 goals in their last 5 matches, underlining their offensive strength.
3. Key Players: Featuring goal-scoring heavyweights like Lionel Messi (19 goals) and Danny Musovski (14 goals), there’s plenty of firepower on both sides to expect goals.

Given these factors, the "Both Teams to Score (Yes)" bet is strongly supported by the teams’ recent performances and key player capabilities, making it a sound choice for punters.

Inter Miami CF vs Seattle Sounders FC Odds

The bookmakers have placed Inter Miami CF as the slight favourites for this face-off against Seattle Sounders FC. With home advantage, Inter Miami are expected to have the edge, particularly with Lionel Messi leading the charge. However, Seattle’s recent form suggests they cannot be counted out easily.

Inter Miami CF vs Seattle Sounders FC Betting Odds
Bet	Odds
Inter Miami CF	1.97
Draw	3.74
Seattle Sounders FC	3.34

With such close odds, it’s clear that this match is expected to be competitive. Inter Miami’s odds reflect their decent home performance, while Seattle’s capability to score prolifically underlines their potential to cause an upset. Punters should consider these odds while also factoring in the recent form and key players for both teams.

Inter Miami CF Team Analysis

Inter Miami CF Recent Performance

Inter Miami CF’s recent form has been a mixed bag with a sequence of wins, draws, and losses in their last five matches. Their notable results include:

• Charlotte FC 3-0 Inter Miami CF (L)
• Seattle Sounders FC 3-0 Inter Miami CF (L)
• Inter Miami CF 3-1 Orlando City (W)
• DC United 1-1 Inter Miami CF (D)
• Inter Miami CF 2-1 Tigres (W)

Recent Form: WDWLL

Inter Miami has struggled defensively, as evidenced by zero clean sheets in their last five games. They have scored an average of 1.20 goals per game during this period but have also shown vulnerabilities, particularly in their last two matches where they conceded three goals each. Despite these setbacks, the presence of top scorer Lionel Messi, with 19 goals so far, continues to give them a potent offensive edge.

Their upcoming match against Seattle Sounders offers a chance to redeem themselves and strengthen their position in the league standings.

Inter Miami CF Key Players

Inter Miami CF boasts a lineup replete with talent, headlined by their top scorer, Lionel Messi, who has netted 19 goals this season. His ability to weave through defenses and create scoring opportunities will be pivotal. Supporting him in the attack is Tadeo Allende, while midfield stalwarts like Rodrigo De Paul and Sergio Busquets provide the creativity and stability.

Expected lineup for Inter Miami CF:

• Goalkeeper: Oscar Ustari
• Defenders: Ian Fray, Gonzalo Luján, Maximiliano Falcón, Jordi Alba
• Midfielders: Rodrigo De Paul, Yannick Bright, Sergio Busquets, Telasco Segovia
• Forwards: Lionel Messi, Tadeo Allende

This ensemble faces a daunting challenge against Seattle’s sturdy defense, but with Messi and Busquets, key individual battles, particularly in the midfield, could tip the scales in Miami’s favor. The outcome may very well hinge on how well these encounters are managed.

Inter Miami CF Suspensions & Injuries

Inter Miami CF will be without some key players due to injuries and suspensions. Notably, Luis Suarez is unavailable due to a post-match sanction, sitting out for three more matches. Tomas Aviles will also miss this game due to a yellow/red card suspension.

In the injury department, the team is missing several crucial players:

• Allen Obando (Hamstring Injury – Expected return late September 2025)
• David Ruiz (Hamstring Injury – Expected return mid-October 2025)
• Baltasar Rodriguez (Hamstring Injury – Expected return mid-October 2025)
• Fafa Picault (Hip injury – Expected return mid-October 2025)

These absences could significantly impact Inter Miami’s defensive and midfield stability, making it challenging for them to maintain a strong lineup. Players like Jordi Alba and Sergio Busquets will need to step up to fill the void left by these absences.

Inter Miami CF Tactics and Formation

Inter Miami CF Tactical Breakdown:

• Formation: 4-4-2
• Key Forward: Lionel Messi
• Midfield Quartet: Rodrigo De Paul, Yannick Bright, Sergio Busquets, Telasco Segovia
• Defensive Concern: No clean sheets in the last five games
• Notable Strategy: Offensive bursts led by Messi and Busquets

Inter Miami CF is expected to deploy a 4-4-2 formation, with an emphasis on leveraging Messi’s attacking prowess. Coaches have placed great faith in Messi, who has been on fire this season with 19 goals. In the midfield, the combination of De Paul, Bright, Busquets, and Segovia provides a balanced mix of creativity, stability, and defensive coverage.

Despite their offensive capabilities, the team struggles defensively, having failed to keep a clean sheet in the last five matches. Coach Javier Mascherano will need to tighten up the backline to avoid conceding early goals. Inter Miami relies heavily on quick, decisive attacking moves, often during the second half.

Seattle Sounders FC Team Analysis

Seattle Sounders FC Recent Performance

Seattle Sounders FC are in a rich vein of form with a fantastic run in their last five outings. Their recent results are:

• Seattle Sounders FC 2-2 LA Galaxy (D)
• Seattle Sounders FC 3-0 Inter Miami CF (W)
• LA Galaxy 0-2 Seattle Sounders FC (W)
• Seattle Sounders FC 5-2 Sporting Kansas City (W)
• Seattle Sounders FC 0-0 Puebla (W on penalties)

Recent Form: WWWWD

Seattle Sounders have showcased their attacking prowess by scoring an impressive average of 3.20 goals per game in their last five matches. Defensively, they’ve managed to keep two clean sheets in these fixtures, indicating a balanced performance on both ends of the pitch. With an unbeaten streak and a recent emphatic win against Inter Miami, they will be keen to continue their momentum. Their form positions them as a formidable opponent even away from home.

Seattle Sounders FC Key Players

Seattle Sounders FC’s key players blend youth and experience, making them a strong unit. Danny Musovski leads the attack with 14 goals this season and will be looking to add more to his tally. In midfield, Cristian Roldan and Jesus Ferreira are essential cogs providing both creative and defensive capabilities.

Expected lineup for Seattle Sounders FC:

• Goalkeeper: Stefan Frei
• Defenders: Alex Roldan, Yeimar Gomez, Jackson Ragen, Reed Baker-Whiting
• Midfielders: Cristian Roldan, Obed Vargas, Kalani Kossa-Rienzi, Jesus Ferreira, Paul Rothrock
• Forward: Danny Musovski

Musovski’s battle against Inter Miami’s central defenders will be crucial, while Jesus Ferreira’s creativity could unlock the Miami defense. This lineup is geared towards maintaining their recent attacking form while ensuring they cover defensively, especially against Miami’s formidable offense steered by Lionel Messi.

Seattle Sounders FC Suspensions & Injuries

Seattle Sounders FC faces several injury challenges heading into this match. Key players out with injuries include:

• Paul Arriola (Cruciate ligament injury – Expected return late November 2025)
• Joao Paulo (Knee injury – Expected return late September 2025)
• Ryan Kent (Hamstring injury – Expected return late September 2025)
• Stuart Hawkins (Hip injury – Expected return late September 2025)
• Pedro De la Vega (Knee injury – Expected return late October 2025)

These injuries could significantly impact Seattle’s midfield and attacking options, as both Joao Paulo and Pedro De la Vega offer substantial creative and scoring threats. Covering these absences will be critical, and Coach Brian Schmetzer will need to rely on the depth of his squad to ensure they maintain their recent good form. No suspensions have been reported for Seattle, allowing them to field their strongest available lineup.

Seattle Sounders FC Tactics and Formation

Seattle Sounders FC Tactical Breakdown:

• Formation: 4-2-3-1
• Key Forward: Danny Musovski
• Midfield Trio: Cristian Roldan, Obed Vargas, Jesus Ferreira
• Defensive Strength: Two clean sheets in the last five games
• Notable Strategy: High pressing and quick transitions

Seattle Sounders FC is expected to line up in a 4-2-3-1 formation, focusing on a balanced approach that combines solid defense with quick transitions to attack. Danny Musovski will lead the line, having scored 14 goals this season, and will be supported by an industrious midfield trio of Cristian Roldan, Obed Vargas, and Jesus Ferreira. Their pressing tactics and ability to execute swift counter-attacks have been key to their recent success.

Despite missing some key players, Seattle’s tactical rigidity and depth in the squad have helped them keep two clean sheets in the last five games. Coach Brian Schmetzer will likely emphasize a cohesive team effort to minimize the impact of their absences.

Inter Miami CF vs Seattle Sounders FC Head-to-Head Statistics

In their recent encounters, Inter Miami CF and Seattle Sounders FC have shared mixed fortunes. Here’s a rundown of their last two meetings:

• Seattle Sounders FC 3-0 Inter Miami CF (1 September 2025, Leagues Cup Final Stage)
• Seattle Sounders FC 0-1 Inter Miami CF (17 April 2022, Major League Soccer)

Seattle Sounders dominated their most recent clash, securing a comprehensive 3-0 victory in the Leagues Cup Final Stage. However, Inter Miami edged out a narrow 1-0 win in their previous Major League Soccer encounter back in 2022.

The overall head-to-head record indicates a tightly contested matchup, with both teams having demonstrated the ability to outplay each other. This upcoming fixture promises another competitive battle, especially with Inter Miami looking to leverage their home advantage and avenge their recent defeat.

Odds accurate as of 15/09/2025 00:33, and are subject to change. Please always check the odds before placing your bets with any bookmaker.